Effect of Sweet potato (Ipomoea batatas (L.) Lam) leaf extract on hypoglycaemia, blood insulin secretion, and key carbohydrate metabolic enzymes in expermentally obese and STZ-induced diabetic mice

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Effect of Sweet potato (Ipomoea batatas (L.) Lam) leaf extract on hypoglycaemia, blood insulin secretion, and key carbohydrate metabolic enzymes in expermentally obese and STZ-induced diabetic mice

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dc.contributor.author Do Ngoc, Lien
dc.contributor.author et al.
dc.date.accessioned 2011-07-28T08:41:42Z
dc.date.available 2011-07-28T08:41:42Z
dc.date.issued 2011-07-28
dc.identifier.issn ISSN 0866-8612
dc.identifier.uri http://tainguyenso.vnu.edu.vn/jspui/handle/123456789/14119
dc.description.abstract Hypolipidemic, hypoglycaemic effects of the ethyl acetate extract fraction from leaves of sweet potato (Ipomoea batatas (L) Lam.) (Convonvulaceae) in obese and streptozotocin (STZ) induced type 2 diabetic mice were demonstrated. When obese-diabetic mice was administrated orally daily by ethyl acetate fraction of 1000mg lyophilized powder/kg for 21 days, we showed that maximum hypoglycaemic(36.77%) and hypolipidemic effects, such as TC(35.18%), TG(29.17%), and LDLc(51.97%) were proven in treated mice compared to the control (untreated mice). The hypoglycaemic effects of ethyl acetate extract fraction from leaves of sweet potato so that it accelerated hexokinase activity, stimulated insulin secretion and inhibited gluconeogenesis enzymatic activity (glucose-6-phosphatase). vi
dc.language.iso en_US vi
dc.relation.ispartofseries 118-124;
dc.subject Ipomoea batatas leaf, obese mice, type 2 Diabetes mellitus, hypolipidemic and hypoglycaemic effect. vi
dc.title Effect of Sweet potato (Ipomoea batatas (L.) Lam) leaf extract on hypoglycaemia, blood insulin secretion, and key carbohydrate metabolic enzymes in expermentally obese and STZ-induced diabetic mice vi
dc.type Article vi

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