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Tai Nguyen So - Vietnam National University, Ha Noi - VNU >
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| Title: | New sesquiterpene from Vietnamese agarwood and its induction effect on brain-derived neurotrophic factor mRNA expression in vitro |
| Authors: | Ueda J.-y.
Imamura L.
Tezuka Y.
Tran Q.L.
Tsuda M.
Kadota S. |
| Keywords: | 2-(2-Phenylethyl)chromone derivative
Agarwood
Brain-derived neurotrophic factor
Spirovetivane-type sesquiterpene
Tram
Vietnamese |
| Issue Date: | 2006 |
| Publisher: | Bioorganic and Medicinal Chemistry |
| Citation: | Volume 14, Issue 10, Page 3571-3574 |
| Abstract: | Agarwood, one of the valuable non-timber products in tropical forest, is a fragrant wood, whose ethereal fragrance has been prized in Asia for incense in ceremony, as well as sedatives in traditional medicine. We separated the 70% EtOH extract of Vietnamese agarwood, which showed significant induction effect on brain-derived neurotrophic factor (BDNF) mRNA expression in rat cultured neuronal cells, to isolate a new compound and a 2-(2-phenylethyl)chromone derivative. The new compound was determined to be a spirovetivane-type sesquiterpene, (4R,5R,7R)-1(10)-spirovetiven-11-ol-2-one, by spectroscopic data and showed induction effect of BDNF mRNA. © 2006 Elsevier Ltd. All rights reserved. |
| URI: | http://tainguyenso.vnu.edu.vn/jspui/handle/123456789/12591 |
| ISSN: | 9680896 |
| Appears in Collections: | Articles of Universities of Vietnam from Scopus
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