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Title: | In vitro antiplasmodial activity of antimalarial medicinal plants used in Vietnamese traditional medicine |
Authors: | Tran Q.L. Tezuka Y. Ueda J.-Y. Nguyen N.T. Maruyama Y. Begum K. Kim H.-S. Wataya Y. Tran Q.K. Kadota S. |
Keywords: | Antimalaria Antiplasmodial FCR-3 Plasmodium falciparum Vietnamese medicinal plants |
Issue Date: | 2003 |
Publisher: | Journal of Ethnopharmacology |
Citation: | Volume 86, Issue 3-Feb, Page 249-252 |
Abstract: | Among 42 extracts, prepared from 14 medicinal plants used in Vietnamese traditional medicine to treat malaria, 24 were found to have antiplasmodial activity by inhibiting the growth of the chloroquine-resistant Plasmodium falciparum strain FCR-3 with EC50 values less than 10μg/ml. Each medicinal plant possessed at least one active extract. The methanol extract of Coscinium fenestratum had the strongest antiplasmodial activity with EC50 value of 0.5μg/ml. Activity-guided fractionation led to identification of berberine as the major active constituent. © 2003 Elsevier Science Ireland Ltd. All rights reserved. |
URI: | http://tainguyenso.vnu.edu.vn/jspui/handle/123456789/12689 |
ISSN: | 3788741 |
Appears in Collections: | Articles of Universities of Vietnam from Scopus
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