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Tai Nguyen So - Vietnam National University, Ha Noi - VNU >
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http://tainguyenso.vnu.edu.vn/jspui/handle/123456789/12988
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| Title: | Chemical constituents of the Vietnamese liverwort Porella densifolia |
| Authors: | Quang D.N.
Asakawa Y. |
| Keywords: | Liverwort
Nitric oxide
Porella densifolia |
| Issue Date: | 2010 |
| Publisher: | Fitoterapia |
| Citation: | Volume 81, Issue 6, Page 659-661 |
| Abstract: | From the ether extract of Porella densifolia, the first liverwort collected and chemically investigated in Vietnam, a kaurane diterpenoid, ent-kauren-15-one (1) and two sesquiterpene norpinguisone (2) and norpinguisone methyl ester (3) have been purified. Their structures were elucidated by spectroscopic analysis. In addition, an X-ray crystal structure of norpinguisone was obtained, allowing to determine its stereochemistry. Furthermore, the inhibitory activity of nitric oxide (NO) production in RAW 264.7 cells stimulated by lipopolysaccharide (LPS) of compounds 1-3 was examined with their IC50 values of 69.4, 45.5 and 1.68 μM, respectively. © 2010 Elsevier B.V. All rights reserved. |
| URI: | http://tainguyenso.vnu.edu.vn/jspui/handle/123456789/12988 |
| ISSN: | 0367326X |
| Appears in Collections: | New - Articles of Universities of Vietnam from Scopus
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