Ergosta Inhibition of nitric oxide Xylaria Xylariaceae
Issue Date:
2008
Publisher:
Natural Product Research
Citation:
Volume 22, Issue 10, Page 901-906
Abstract:
From the methanolic extract of Xylaria sp. collected in Vietnam, a fluorescent constituent, ergosta-4,6,8(14),22-tetraen-3-one (1) was isolated and elucidated by the combination of 2D NMR, high resolution MS, IR and UV spectroscopy. Its inhibitory activity of nitric oxide production in RAW 264.7 cells stimulated by lipopolysaccharide was examined and showed a potential activity with the IC50 value of 28.96 μM.
