diterpene diterpenoid flavone genkwanin labdane leoheteronin Leonurus heterophyllus extract phytosterol plant extract sitosterol stigmasterol unclassified drug angiosperm article chemical structure chemotaxonomy drug isolation Leonurus Viet Nam Magnetic Resonance Spectroscopy
Issue Date:
2005
Publisher:
Chemical and Pharmaceutical Bulletin
Citation:
Volume 53, Issue 8, Page 938-941
Abstract:
Five new natural labdane-type diterpenoids (5-9), designated leoheteronins A-E, together with four
known diterpenoids (1-4), two phytosterols as a mixture of ?-sitosterol and stigmasterol, and the flavone
genkwanin (10) were isolated from the aerial parts of Leonurus heterophyllus SW. (Lamiaceae) collected in
northern Vietnam. Compound 1 was isolated for the first time from a Leonurus species, and 10 is considered
to be a chemotaxonomic marker of the Leonurus genus. Their structures were determined using
spectroscopic analyses. ?? 2005 Pharmaceutical Society of Japan.
