Thirteen new substituted acetophenone (2,3,4,6-tetra-O-acetyl-?-Dglucopyranosyl)-
thiosemicarbazones (3) were synthesized by reaction of 2,3,4,6-tetra-O-acetyl-?-D-glucopyranosyl
thiosemicarbazide (1) and substituted acetophenones (2). The reaction was performed using
microwaveassisted method. The compounds (3) have remarkable antibacterial and antifungal activities
against Escherichia coli, Staphylococcus epidermidis and Candida albicans.