A Fe3O4 based magnetic fluid with different concentrations ranged between 0.15 ng/cell to 10
ng/cell (nano gram/cell) was used in the in vitro toxicity test on several cancer cell lines, Sarcoma 180, HeLa
and H358. It shows that the fluid with a concentration of Fe 3O4 below 1.2 ng/cell is completely non-toxic
for these cell lines. Even through in the presence of the highest concentration of 10 ng/cell, the cell viability
still reaches more than 60%. The magnetic fluid with Fe3O4 concentration of about 0.1 ng/cell was also
used to search ex-vivo the possibility of Sarcoma 180 extermination by magnetic heating with an AC field
of 120Oe and 184 KHz. The result shows that after a heat treatment for 30 min., 40% of Sarcoma 180 cells
was killed. ?? 2009 IOP Publishing Ltd.
